Superior Vena Cava (SVC) Syndrome 

Definition: 

SVC syndrome is a condition where blood flow through the superior vena cava (SVC), the large vein that carries blood from the head, neck, and upper body to the heart, is obstructed

Causes: 

  • Cancer:Lung cancer, lymphoma, and other mediastinal tumors are the most common causes.Â
  • Blood clots:Deep vein thrombosis (DVT) or central venous catheter-related thrombosis can block the SVC.Â
  • Other:Infections, trauma, and certain medical devices (e.g., pacemakers) can also cause SVC syndrome.Â

Symptoms: 

  • Swelling of the face, neck, and upper body
  • Distended veins in the neck and chest
  • Shortness of breath
  • Cough
  • Difficulty swallowing
  • Headache
  • Confusion or altered mental status (in severe cases)Â

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