Allergic bronchopulmonary aspergillosis (ABPA) is a condition caused by a hypersensitivity reaction to the fungus Aspergillus fumigatus, commonly found in soil, decaying vegetation, and indoor environments. It primarily affects people with asthma or cystic fibrosis, leading to airway inflammation, mucus buildup, and potential lung damage if untreated.
Key Features:
- Symptoms: Wheezing, coughing, shortness of breath, chest pain, fatigue, and sometimes fever or coughing up blood.
- Diagnosis: Based on clinical history, imaging (chest X-ray or CT showing bronchiectasis), and tests like elevated IgE levels, positive Aspergillus-specific IgE or IgG, and eosinophilia.
- Risk Factors: Asthma (especially severe or poorly controlled), cystic fibrosis, or other lung conditions.
- Complications: If untreated, can lead to bronchiectasis, pulmonary fibrosis, or chronic lung damage.
Treatment:
- Corticosteroids: To reduce inflammation (e.g., prednisone).
- Antifungal agents: Itraconazole or voriconazole to reduce fungal load.
- Bronchodilators: For asthma-like symptoms.
- Management of underlying conditions: Optimizing asthma or cystic fibrosis treatment.
Prevention:
- Avoid exposure to moldy environments.
- Use air filtration systems.
- Regular monitoring for those with asthma or cystic fibrosis.
For more details or personalized advice, consult a pulmonologist or allergist.
Disclaimer: owerl is not a doctor; please consult one.
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