Erythema multiforme is a skin disorder characterized by a rash with target lesions (lesions with a bull’s-eye appearance). It’s often triggered by infections, like the herpes simplex virus, or medications. The rash can be mild or severe, sometimes involving mucous membranes in the mouth, eyes, or genitals.
Here’s a more detailed look:
Symptoms:
Target lesions: These are the hallmark of erythema multiforme, appearing as red, raised spots with a dark center and a lighter ring around it.
Rash: The rash can appear on the hands, feet, arms, and legs, but can spread to the face, neck, and body.
Pain and itching: The lesions may be painful or itchy.
Mucosal involvement: In more severe cases, sores can appear in the mouth, eyes, or genitals.
Fever and joint pain: These can be present in more severe cases.
Causes:
Infections:
Herpes simplex virus (the virus that causes cold sores) is a common trigger, but other viruses and bacteria can also cause erythema multiforme.
Medications:
Some medications, like certain antibiotics, anti-inflammatories, and anticonvulsants, can also trigger it.
Underlying conditions:
In rare cases, erythema multiforme can be linked to other medical conditions, such as Behcet’s disease or lupus.